Mathematical Model for Stiffness and Energy of Extracellular Matrix in the Growth of Cancer

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Published: 2024-12-15
Keywords:
Infection proportion, tumor mass, velocity of growth, potential and kinetic energy, machine learning

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Ganesh Prasad Pokhariyal
Department of Mathematics, Graphic Era Hill University, Dehradun, India
Nilesh Patel
Department of Medical Physiology, University of Nairobi, Kenya
Sudhakar Chaubey
Section of Mathematics, Department of Information Technology, University of Technology and Applied Sciences, Shinas, Oman

Abstract

Stiffness of Extracellular matrix (briefly, ECM) plays an important role in providing a tumor microenvironment and the increased stiffness has been associated with the development of tumor. The notions of potential energy and kinetic energy are developed and used to explain the growth of cancer from incubation stage to the asymptotic stage by maintaining the law of conservation of energy. The product of model parameters ,  and  is shown to be constant, which reflects their complimentary nature for the growth of cancer in patients and can be used to formulate control strategies for treatment.

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Vol. 28 No. 4 (2024): Table of Content

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1.
Mathematical Model for Stiffness and Energy of Extracellular Matrix in the Growth of Cancer. J. Int. Acad. Phys. Sci. [Internet]. 2024 Dec. 15 [cited 2026 Oct. 23];28(4):277-8. Available from: http://www.iaps.org.in/journal/index.php/journaliaps/article/view/1022

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